Nanoparticles Reviews

An introduction to novel LNP targeting strategies for optimizing RNA-LNP biodistribution and improving cell specificity

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RNA therapeutics: From concept to clinical reality Over the past decade, RNA therapeutics have moved from theoretical…

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RNA Transfection Methods: Comparative Overview

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Introduction RNA transfection has become a vital tool for studying gene expression and regulating immune cell…

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Self‑Amplifying RNA versus Conventional mRNA – A Forward‑Looking Comparison

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Why Move Beyond First‑Generation mRNA? Self-amplifying RNA (saRNA) represents a promising evolution beyond…

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What are lipid-based nanoparticles?

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Over the past three decades, the development of lipid-based nanoparticles (LBNPs) technologies as a carrier for drug…

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Understanding the key role of Ionizable Lipids in novel RNA-lipid nanoparticle therapies

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The astonishing rapidity of COVID-19 mRNA-LNP vaccine development surprised the global community. One of the primary…

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Solid lipid nanoparticles: an introduction

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Over the last few decades, the significance of lipid-based nanoparticles (LBNs) development has greatly…

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RNA-LNP vaccines: The Role of Lipid Nanoparticle Compositions

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Lipid nanoparticles (LNPs) have emerged as a revolutionary tool in the biotechnology field, particularly for the…

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RNA-LNP Morphology: A Comprehensive Review

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Understanding RNA-LNP Morphology  The development of RNA-lipid nanoparticles (RNA-LNPs) presents a significant…

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Microfluidic synthesis of lipid nanoparticles

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Why using microfluidics ? The microfluidic synthesis of lipid nanoparticles has recently been brought to the spotlight…

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Mastering Thin Film Hydration Method for Liposome and Lipid Nanoparticle Formulation

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Thin Film Hydration, the genesis of liposomes and Lipid nanoparticles The Thin Film Hydration Method is a…

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LNP and liposomes characterization guidelines

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In the fast-paced biotechnology landscape, LNP characterization, and more generally characterization of lipid-based…

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Liposomes vs Lipid Nanoparticles as vehicles for delivery applications

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As several kinds of lipid-based nanoparticles (LBNPs) are currently available for delivering small molecules,…

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Lipid-based nanoparticles drug delivery for cancer therapies

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In the ever-evolving landscape of cancer-therapies, the convergence of cutting-edge nanoparticles technology and health…

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Lipid Nanoparticle for mRNA delivery

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In the realm of cutting-edge medical advancements, the use of lipid nanoparticles for mRNA (messenger RNA) delivery…

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Introduction to PLGA Nanoparticles as a Drug Delivery System

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For the past decades, modern medicine shifted more and more towards the use of nanocarriers as drug delivery systems…

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How to optimize lipid nanoparticle formulation?

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The optimization of lipid nanoparticle formulation (LNP) stands as a critical pursuit for the next generation of RNA…

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Fundamentals of microfluidic mixing for LNP synthesis

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The recent progress of microfluidics mixing technologies (micromixers) has been key to the recent success of the…

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Fundamentals of lipid nanoparticles formation mechanism by nanoprecipitation

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Lipid nanoparticle formation mechanisms, also referred to as nanoprecipitation or nanoparticle self-assembly methods,…

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Exploring LNP Size and its Significance in Drug Delivery

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The development of advanced drug delivery systems, such as lipid nanoparticles (LNP) has revolutionized modern…

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Dialysis: a key and underestimated factor for the synthesis of lipid nanoparticle by microfluidics

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This research summary aims at describing the influence of the critical process parameters on the main characteristics…

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